Description
Product Characteristics: OSBP2, ORP-4, OSBPL1, KIAA1664, oxysterol binding protein 2, oxysterol binding protein-like 1, ORP4, OSBPL4, OSBP-related protein 4, oxysterol binding protein-related protein 4
Target Information: Oxysterols are byproducts of cholesterol that can have cytotoxic effects on many cell types. The membrane-bound protein encoded by this gene contains a pleckstrin homology (PH) domain and an oxysterol-binding region. It binds oxysterols such as 7-ketocholesterol and may inhibit their cytotoxicity. Alternate transcriptional splice variants have been observed but have not been fully characterized. [provided by RefSeq, Jul 2008]